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Recommendations on vitamin and mineral supplementation for children and adults with autism.

Based on 20 years of research

Vitamin and mineral supplementation is essential for human health, and even more necessary for individuals with autism spectrum disorder:

  • Many children and adults with ASD have poor diets with low amounts of vegetables, fruit, and/or protein
  • Most children and adults with ASD also have metabolic issues including mitochondrial dysfunction, oxidative stress, low glutathione, and abnormal neurotransmitters



Pilot study of a moderate dose multivitamin/mineral supplement for children with autistic spectrum disorder

Randomized, double-blind, placebo-controlled 3-month study of twenty (20) children with Autism Spectrum Disorder, ages 3-8 years.

Results: A Global Impressions parental questionnaire found that the supplement group reported statistically significant improvements in sleep and gastrointestinal problems.

link View Study and Conclusions

Significant Improvements in Sleep and Gastrointestinal Problems

cerecell benefits

Parental Global Impressions – Average

Parental Global Impressions


Effect of a vitamin/mineral supplement on children and adults with autism

Randomized, double-blind, placebo-controlled 3-month study of 141 children and adults with autistic spectrum disorder.

Results: Supplement significantly improved nutritional status, metabolic problems, and overall ASD symptoms. Treatment group did better than placebo on all scores, with significantly better improvements on Average Score, Receptive Language, Hyperactivity, Tantrumming, and Overall.

link View Study and Conclusions


Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder—A Randomized, Controlled 12-Month Trial

Vitamin/mineral supplement combined with 5 other nutritional/dietary interventions in 12 month randomized controlled trial of 67 children and adults with ASD.

Combined treatment resulted in many benefits, including:

  • 7 point gain in 1Q vs. O for control group
  • 18 month gain in developmental age vs 4 months for control group

Vitamin/mineral supplement rated along with fish oil as top 2 of 6
nutritional treatments

  • 11% much better, 33% better, 44% slightly better, 11% no change
  • 85% of participants wanted to continue vitamin/mineral supplement at end of study

link View Study and Conclusions

Behavioral Changes – % Improvement

Developmental Gains in Years



73% chance of moderate, good, or great benefit

2022 Research survey of 161 children and adults with ASD who had used the supplement treatment for 3 or more months (average 12 months)

Statistically significant improvements in:

  • Overall autism symptoms
  • Language
  • Cognition
  • Play
  • Eye contact
  • Sleep
  • Tantrums/meltdowns
  • Hyperativity

73% reported moderate to great improvement, 19% reported a slight benefit, and only 8% reported no benefit.


Cerecell Spectrum Enhanced Nutritional Supplementation

Based on these previous studies, we modified the vitamin/mineral formulation and developed Cerecell Spectrum Enhanced Nutritional Supplementation

Special features include:

  • Comprehensive vitamin/mineral supplement, at optimal levels based on pre/post testing in our clinical trials
  • Highly absorbable forms of vitamins and minerals
  • Mitochondrial support – including CoQ10, carnitine, and other nutrients
  • Oxidative stress support – including NADH to recycle glutathione, the primary anti-oxidant
  • Methylation support – MTHF and vitamin B12
  • Sulfate – provides sulfate, the 4th most common mineral in the body, and which is 65% lower in children with ASD.
  • Lithium – provides a small dose to restore normal levels of lithium, which is 52% lower in children with ASD

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